The Low-fitness Phenotype as a Risk Factor: More Than Just Being Sedentary?

It's More Than Just Being Connected

ERCP in the elderly: more than just the age factor.

322 and family) of good end of life care. Currently the physician may ‘inadvertently fall into the trap of prognostic paralysis’ [1]. The clinical question ‘would I be surprised if this patient died within the next year’ has been advocated as a useful prompt for care planning, discussion with the patient and family, and in decision making [4]. COPD is a chronic incurable disease, and many patie...

PDGF in gliomas: more than just a growth factor?

Platelet-derived growth factor B (PDGF-B) is a growth factor promoting and regulating cell migration, proliferation, and differentiation, involved in both developmental processes and in maintaining tissue homeostasis under strict regulation. What are the implications of prolonged or uncontrolled growth factor signaling in vivo, and when does a growth factor such as PDGF-B become an oncogene? Un...

More than just vanilla.

SIDS Risk: It's More Than Just the Sleep Environment.

It is widely acknowledged that dramatic declines in the rate of sudden infant death syndrome (SIDS) in the United States resulted from recommendations that infants not be placed prone to sleep, first by the American Academy of Pediatrics in 1992,1 followed by the national Back to Sleep campaign 2 years later.2 Other recommendations, such as room-sharing without bed-sharing and avoidance of soft...